Can you reverse ageing?
You may not be able to reverse it entirely, but you can slow it. And increasingly, science is showing us how.
The field of longevity research is advancing at a remarkable pace. One of the most exciting breakthroughs lies in our understanding of a vital cellular molecule: NAD+ (nicotinamide adenine dinucleotide). Levels of NAD+ decline with age, and that decline is now recongized as a driving factor in the ageing process itself. The good news? We can support its restoration through a compound called nicotinamide riboside (NR). These are damaged, lingering cells that disrupt tissue health and accelerate biological ageing. And remarkably, some of the most effective senolytics are derived from nature.
What is NAD and Why Does It Matter?
NAD+ is a coenzyme found in every cell of the body, playing a critical role in energy metabolism, DNA repair, mitochondrial function and cellular resilience. As we age, NAD+ levels fall dramatically, by as much as 50% compromising the cells ability to repair and renew.
The decline contributes to fatigue, cognitive decline and reduced metabolic efficiency and increased susceptibility to age-related diseases.
Nicotinamide Riboside: A Proven NAD+ Precursor
NR is a form of Vitamin B3 that the body efficiently converts into NAD+. Supplementation has been shown to:
Elevate cellular NAD+ levels
Support mitochondrial health and energy metabolism
Enhance cellular repair processes
Improve brain, muscle and metabolic function in ageing populations.
Unlike some NAD+ precursors, NR is well-tolerated and backed by clinical studies making it one of the most advanced tools for supporting longevity at the cellular level.
For further reading:
Dellinger et al. (2017)
Nanga et al. (2024)
Henderson et al. (2024)
Simon et al. (2024)